I've not really had much success with CareerBuilder. I get automated emails after applying thanking me for my interest, but I have never had a callback for an interview for any job I've applied to. I get a lot of solicitors who say they got my resume from CareerBuilder offering me the chance to go to work selling insurance for some insurance company no one has ever heard of. I'm sitting here right now trying to think of one job interview that has come about as a result of a job I was interested in and applied to, but I can't think of any.
